AXL-MBIP/BaF3
CBP73274
| I. Introduction | |
| Cell Line Name: | AXL-MBIP/BaF3 | 
| Host Cell: | Ba/F3 | 
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) | 
| Freeze Medium: | 90% FBS+10% DMSO | 
| Complete Culture Medium: | RPMI-1640+10%FBS | 
| Mycoplasma Status: | Negative | 
| II. Background | |
| AXL, AXL receptor tyrosine kinase, is a receptor tyrosine kinase, which promotes growth, migration, and survival of tumor cells through activation of Mapk signaling (PMID: 28072762). Activation and overexpression of AXL has been associated with resistance to chemotherapeutic agents and targeted therapies (PMID: 28251492), in both solid and hematological tumors (PMID: 32148495). | |
| III. Representative Data | |
| 1. WB of AXL-MBIP/BaF3 
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| 2. Anti-proliferation assay | |
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| Figure 2. CTG Proliferation Assay of BaF3 AXL MBIP (C2). | |
 
            

 
             
             
         
             
             
             
             
             
             
            